SCHEMBL25849609

SCHEMBL25849609

CN1/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)N(c2c(Cl)cccc2Cl)c2nc3ccccc3nc21

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 10/20 0.33
ILF3 Q12906 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CASP1 P29466 1/20 0.31
HTT P42858 1/20 0.31
CASP7 P55210 1/20 0.31
HBB P68871 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849608 0.88 ALDH1A1 (0.37) ILF3KDM4EALDH1A1
SCHEMBL25849611 0.87 PDE7A (0.32) ILF3
SCHEMBL25849554 0.85 DPP4 (0.36) ILF3
SCHEMBL25849603 0.85 ILF3 (0.32) ILF3KDM4EALDH1A1HTT
SCHEMBL25849612 0.85 ILF3 (0.39) ILF3KDM4EALDH1A1
SCHEMBL25849601 0.84 ILF3 (0.34) ILF3KDM4EALDH1A1HTT
SCHEMBL25849589 0.84 DPP4 (0.34)
SCHEMBL25849849 0.83 ELANE (0.40) MAPK14KDM4EALDH1A1CASP1HTT
SCHEMBL23337553 0.78 KDM4E (0.42) KDM4EALDH1A1
SCHEMBL23337591 0.78 DPP4 (0.39) ILF3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed