SCHEMBL25850274

SCHEMBL25850274

CCCCCCCCCCCCCCCC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CC(C)(C)COCC(C)(C)CNC(=O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(=O)NCC(C)(C)COCC(C)(C)CC(=O)NCC(C)(C)COCC(C)(C)CNC(=O)CCCCCCCCCCCCCCC)C(=O)c1ccc(C#CC#N)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.32
CNR2 P34972 2/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850207 0.77 DNM1 (0.34) CNR1CNR2
SCHEMBL26037626 0.75
SCHEMBL26050598 0.70
SCHEMBL24341855 0.69 FAAH (0.44) CNR1CNR2MEN1KMT2A
SCHEMBL25850206 0.68 FAAH (0.43) CNR1CNR2
SCHEMBL16377586 0.68 EPHX2 (0.45) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL18897623 0.68 EPHX2 (0.45) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL26035258 0.68 CNR1 (0.38) CNR1CNR2MEN1ALDH1A1MAPT
SCHEMBL16377524 0.67 SELP (0.47) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL21096814 0.67 FAAH (0.46) CNR1CNR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS Arrowhead Pharmaceuticals, Inc. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226193-A1 LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS CPT1B, MUSK, MYLK2 CNR1 4510/4885CNR2 4584/4885MEN1 4753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.