Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | DTYMK | P23919 | 4/20 | 0.52 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.48 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23477159 | 0.92 | RNASEL (0.56) | TGM2DTYMKFUT5RNASEL | |
| SCHEMBL24771772 | 0.92 | RNASEL (0.56) | TGM2DTYMKFUT5RNASEL | |
| SCHEMBL19696038 | 0.87 | RNASEL (0.61) | RNASEL | |
| SCHEMBL22080410 | 0.87 | NT5E (0.51) | TGM2DTYMKFUT5P2RY1P2RY2 | |
| SCHEMBL25552773 | 0.87 | TGM2 (0.60) | TGM2FUT5P2RY2NT5ERNASEL | |
| SCHEMBL20762949 | 0.85 | DNPH1 (0.55) | DTYMKFUT5P2RY1P2RY2NT5E | |
| SCHEMBL27378469 | 0.85 | RNASEL (0.67) | TGM2P2RY1P2RY2NT5ESRC | |
| SCHEMBL19696031 | 0.85 | DTYMK (0.62) | DTYMKP2RY2RNASEL | |
| SCHEMBL23477028 | 0.84 | FUT5 (0.58) | TGM2FUT5P2RY2NT5EP2RX3 | |
| SCHEMBL23476675 | 0.84 | NT5E (0.53) | TGM2FUT5P2RY2NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | TGM2 3514/4885DTYMK 2045/4885FUT5 3130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.