SCHEMBL25853304

SCHEMBL25853304

C=CC(=O)Oc1ccc2c(c1)sc1c(OC(F)(F)F)c(OC(=O)C=C)ccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.35
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
DYRK1A Q13627 1/20 0.32
THRB P10828 1/20 0.31
TUBB4A P04350 2/20 0.31
TUBB P07437 2/20 0.31
TUBA3C P0DPH7 2/20 0.31
TUBA1B P68363 2/20 0.31
TUBA4A P68366 2/20 0.31
TUBB4B P68371 2/20 0.31
TUBB3 Q13509 2/20 0.31
TUBB2A Q13885 2/20 0.31
TUBB8 Q3ZCM7 2/20 0.31
TUBA3E Q6PEY2 2/20 0.31
TUBA1A Q71U36 2/20 0.31
TUBA1C Q9BQE3 2/20 0.31
TUBB6 Q9BUF5 2/20 0.31
TUBB2B Q9BVA1 2/20 0.31
TUBB1 Q9H4B7 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856161 0.91 ESR1 (0.39) ESR1THRB
SCHEMBL25854311 0.88 TYMS (0.35) THRBTYMS
SCHEMBL25854666 0.86 ESR1 (0.38) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25853231 0.85 TUBB4A (0.41) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25853239 0.84 ALDH1A1 (0.33) ESR1THRBTYMSALDH1A1
SCHEMBL25853306 0.83 DYRK1A (0.35) ESR1CCNCCDK8DYRK1ATUBB4A
SCHEMBL25853852 0.82 TYMS (0.32) THRBTYMS
SCHEMBL25853529 0.82 TYMS (0.32) TYMS
SCHEMBL25853135 0.82 THRB (0.34) THRBTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL25853708 0.81 TYMS (0.32) THRBTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed