SCHEMBL25854666

SCHEMBL25854666

C=CC(=O)Oc1ccc(-c2ccc3c(sc4cc(OC(=O)C=C)ccc43)c2OC(F)(F)F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.38
SCN5A Q14524 2/20 0.32
SCN9A Q15858 1/20 0.32
FFAR1 O14842 2/20 0.32
FFAR4 Q5NUL3 2/20 0.32
THRB P10828 1/20 0.32
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31
TUBB8 Q3ZCM7 1/20 0.31
TUBA3E Q6PEY2 1/20 0.31
TUBA1A Q71U36 1/20 0.31
TUBA1C Q9BQE3 1/20 0.31
TUBB6 Q9BUF5 1/20 0.31
TUBB2B Q9BVA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25854669 0.88 THRB (0.37) ESR1SCN5AFFAR1FFAR4THRB
SCHEMBL25856373 0.86 FFAR4 (0.33) ESR1SCN5ASCN9AFFAR1FFAR4
SCHEMBL25853304 0.86 ESR1 (0.35) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25854568 0.86 TUBB4A (0.42) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25854668 0.85 ELANE (0.34) ESR1SCN5ASCN9AFFAR1FFAR4
SCHEMBL25854576 0.85 ESR1 (0.33) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25854438 0.84 THRB (0.35) ESR1THRBTUBB4ATUBBTUBA3C
SCHEMBL25856161 0.84 ESR1 (0.39) ESR1THRB
SCHEMBL25854949 0.83 FFAR4 (0.31) ESR1FFAR1FFAR4THRB
SCHEMBL25856104 0.82 FFAR4 (0.31) ESR1FFAR4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed