SCHEMBL25856161

SCHEMBL25856161

C=CC(=O)Oc1ccc(-c2ccc3c(c2)sc2c(OC(F)(F)F)c(OC(=O)C=C)ccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.39
CTSA P10619 1/20 0.33
PIM1 P11309 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
THRB P10828 1/20 0.31
TEK Q02763 1/20 0.31
AURKA O14965 1/20 0.31
TPX2 Q9ULW0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25853304 0.91 ESR1 (0.35) ESR1THRB
SCHEMBL25855448 0.86 TUBB4A (0.39) ESR1THRB
SCHEMBL25856163 0.86 THRB (0.33) ESR1THRB
SCHEMBL25855861 0.85 ESR1 (0.34) ESR1THRB
SCHEMBL25856373 0.85 FFAR4 (0.33) ESR1THRBTEK
SCHEMBL25856162 0.84 KMT2A (0.35) ESR1CTSAPIM1PIM2
SCHEMBL25854666 0.84 ESR1 (0.38) ESR1THRB
SCHEMBL25854311 0.84 TYMS (0.35) THRB
SCHEMBL25854768 0.84 THRB (0.34) ESR1THRB
SCHEMBL25856165 0.83 FFAR4 (0.32) ESR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134598-A1 POLYMERISABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134596-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed