Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17071834 | 0.80 | ABCB11 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16770774 | 0.80 | ABCB11 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL16952371 | 0.80 | CNR2 (0.31) | CNR2KDM4EALDH1A1POLBGAA | |
| SCHEMBL25857978 | 0.77 | ABCB11 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7634231 | 0.76 | TSHR (0.44) | CNR2KDM4EALDH1A1POLBGAA | |
| SCHEMBL28599339 | 0.76 | CNR2 (0.39) | CNR2KDM4EALDH1A1POLBGAA | |
| SCHEMBL16952302 | 0.75 | CNR2 (0.37) | CNR2KDM4EALDH1A1POLBGAA | |
| SCHEMBL18893300 | 0.74 | ALDH1A1 (0.37) | ALDH1A1GAAGABRA1GABRB1NR3C1 | |
| SCHEMBL10130853 | 0.73 | LPL (0.45) | CNR2ABCB11CNR1 | |
| SCHEMBL25857242 | 0.73 | ABCB11 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135233-A1 | AZAINDOLE DERIVATIVES AND THEIR USE AS ERK KINASE INHIBITORS | AGV DISCOVERY (FR) | 2023-07-20 | — | — | WO | disclosed |