Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839394 | 0.57 | SMN1; SMN2 (0.50) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL6283202 | 0.57 | MMP1 (0.67) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11686001 | 0.55 | SMN1; SMN2 (0.62) | KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL10001 | 0.54 | — | — | |
| SCHEMBL28060459 | 0.54 | ALDH1A1 (1.00) | KDM4E | |
| SCHEMBL3025923 | 0.53 | NPC1 (0.67) | KDM4EHPGDSMN1; SMN2 | |
| Alcohol SCHEMBL137775 | 0.52 | ALDH1A1 (0.77) | — | |
| SCHEMBL27722569 | 0.52 | — | — | |
| SCHEMBL6801343 | 0.52 | — | — | |
| SCHEMBL11615492 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | MERCK SHARP & DOHME LLC (US) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702430-B2 | Aza-benzothiophene compounds as STING agonists | STING1, IRF3, CGAS | STING1 1/4885KDM4E 760/4885HPGD 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.