Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119181 | 0.87 | TSHR (0.38) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL25856382 | 0.85 | TACR1 (0.31) | — | |
| SCHEMBL29317328 | 0.84 | — | — | |
| SCHEMBL24480971 | 0.83 | CHRM5 (0.38) | KMT2ACHRM5ADRA2CHPGDHRH3 | |
| SCHEMBL13190119 | 0.81 | HTR6 (0.41) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL29317239 | 0.80 | ACHE (0.41) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL24480840 | 0.80 | L3MBTL3 (0.33) | MEN1ALDH1A1CYP2C9TSHRCYP2C19 | |
| SCHEMBL25856205 | 0.78 | GBA1 (0.35) | KMT2AHPGDHRH3 | |
| SCHEMBL25027122 | 0.78 | NCF1 (0.37) | ALDH1A1KMT2ACHRM5ADRA2CHPGD | |
| SCHEMBL25856575 | 0.78 | NCF1 (0.37) | ALDH1A1KMT2ACHRM5ADRA2CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131167-A1 | COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 海思科医药集团股份有限公司 | 2023-07-13 | — | — | WO | disclosed |