SCHEMBL25856382

SCHEMBL25856382

CN1CC2(CCC(N3CCC(CN4CCNCC4)CC3)CC2)C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25856391 0.85 MEN1 (0.33)
SCHEMBL24480580 0.83 GNAO1 (0.34)
SCHEMBL25856575 0.82 NCF1 (0.37)
SCHEMBL25027122 0.82 NCF1 (0.37)
SCHEMBL24480581 0.81 NCF1 (0.34)
SCHEMBL25856385 0.81
SCHEMBL25856205 0.80 GBA1 (0.35) TACR1
SCHEMBL29317328 0.80
SCHEMBL24480751 0.79 GBA1 (0.33) TACR1
SCHEMBL24866010 0.79 GBA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131167-A1 COMPOUND FOR INHIBITING AND DEGRADING IRAK4, AND PHARMACEUTICAL COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF 海思科医药集团股份有限公司 2023-07-13 WO disclosed