⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856391 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL25856382 | 0.80 | TACR1 (0.31) | — | |
| SCHEMBL24480971 | 0.77 | CHRM5 (0.38) | — | |
| SCHEMBL25856205 | 0.73 | GBA1 (0.35) | — | |
| SCHEMBL25856575 | 0.72 | NCF1 (0.37) | — | |
| SCHEMBL25027122 | 0.72 | NCF1 (0.37) | — | |
| SCHEMBL29317239 | 0.71 | ACHE (0.41) | — | |
| SCHEMBL25856385 | 0.71 | — | — | |
| SCHEMBL27119181 | 0.71 | TSHR (0.38) | — | |
| SCHEMBL24480965 | 0.71 | KMT2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |