SCHEMBL25857161

SCHEMBL25857161

C=CC1OC(C=C)C2C(=O)N(CCN/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)C12

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
AKT1 P31749 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857182 0.88 ALDH1A1 (0.42) AKT1ALDH1A1
SCHEMBL25857174 0.85 ALDH1A1 (0.45) AKT1ALDH1A1
SCHEMBL25857137 0.85 OPRM1 (0.41) AKT1ALDH1A1
SCHEMBL19388140 0.85 OPRM1 (0.41) AKT1ALDH1A1
SCHEMBL24669254 0.71 TDP1 (0.34) KDM4E
SCHEMBL6859236 0.71 TDP1 (0.34) KDM4E
SCHEMBL23900875 0.71 ZDHHC20 (0.36) ALDH1A1
SCHEMBL22100058 0.70 OPRM1 (0.43) ALDH1A1
SCHEMBL22130596 0.70 OPRM1 (0.32) AKT1ALDH1A1
SCHEMBL22863834 0.70 OPRM1 (0.47) AKT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 KDM4E 1552/4885AKT1 4171/4885ALDH1A1 1829/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 KDM4E 1552/4885AKT1 4171/4885ALDH1A1 1829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.