SCHEMBL25857182

SCHEMBL25857182

C=CC1OC(/C=C\C2OC(C=C)C3C(=O)N(Cc4ccccc4)C(=O)C23)C2C(=O)N(CCN/C(=N\C(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)C12

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
AKT1 P31749 2/20 0.37
NPFFR1 Q9GZQ6 5/20 0.33
NPFFR2 Q9Y5X5 5/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP2D6 P10635 2/20 0.32
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
NPY1R P25929 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857161 0.88 KDM4E (0.32) ALDH1A1AKT1
SCHEMBL25857174 0.86 ALDH1A1 (0.45) ALDH1A1AKT1KMT2A
SCHEMBL19388140 0.77 OPRM1 (0.41) ALDH1A1AKT1MAPT
SCHEMBL25857137 0.77 OPRM1 (0.41) ALDH1A1AKT1MAPT
SCHEMBL25857181 0.76 ALDH1A1 (0.38) ALDH1A1KMT2AMAPT
SCHEMBL24746656 0.72 ALDH1A1 (0.45) ALDH1A1AKT1
SCHEMBL24746668 0.71 ALDH1A1 (0.44) ALDH1A1AKT1
SCHEMBL24746667 0.70 ALDH1A1 (0.43) ALDH1A1AKT1
SCHEMBL24747003 0.69 ALDH1A1 (0.43) ALDH1A1AKT1
SCHEMBL25857056 0.68 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885AKT1 4171/4885NPFFR1 4135/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885AKT1 4171/4885NPFFR1 4135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.