Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MECP2 | P51608 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921664 | 0.81 | HSD17B1 (0.45) | MAP4K4CYP3A4MKNK1MKNK2CA12 | |
| SCHEMBL11512521 | 0.81 | MAP4K4 (0.46) | MAP4K4MAOACYP3A4CASP1RECQL | |
| SCHEMBL11514349 | 0.81 | MAP4K4 (0.50) | MAP4K4MAOACYP3A4CASP1RECQL | |
| SCHEMBL3085799 | 0.80 | MAP4K4 (0.41) | MAP4K4MAOACYP3A4MEN1PSIP1 | |
| SCHEMBL7393282 | 0.79 | ALDH1A1 (0.50) | MAP4K4CYP3A4ALDH1A1LMNAHPGD | |
| SCHEMBL5187958 | 0.78 | CYP3A4 (0.42) | CYP3A4MEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL8490974 | 0.78 | PRKCI (0.44) | ENPP2IKBKB | |
| SCHEMBL29471388 | 0.77 | MAOA (0.68) | MAP4K4MAOACYP3A4CASP1RECQL | |
| SCHEMBL2023695 | 0.77 | MAOA (0.68) | MAP4K4MAOACYP3A4CASP1RECQL | |
| SCHEMBL2442271 | 0.74 | MAOA (0.65) | MAP4K4MAOACYP3A4CASP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066647-B1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2011-11-09 | — | — | EP | claimed |