SCHEMBL25858222

SCHEMBL25858222

CCC(=O)NC(C)Cc1ccc2c(c1)OCO2

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.63
SLC6A4 P31645 3/20 0.63
SLC6A2 P23975 2/20 0.63
SLC6A3 Q01959 2/20 0.63
CYP2D6 P10635 2/20 0.63
ACACB O00763 1/20 0.57
HPGD P15428 2/20 0.52
CYP3A4 P08684 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HSD17B10 Q99714 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11697049 0.90 TAAR1 (0.60) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL24218807 0.88 TAAR1 (0.62) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL15624537 0.88 TAAR1 (0.62) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL25391470 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL25201048 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL11745127 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL25391472 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL26238861 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL26983120 0.86 TAAR1 (0.67) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6
SCHEMBL28939114 0.85 TAAR1 (0.62) TAAR1SLC6A4SLC6A2SLC6A3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060991-A1 METHODS AND COMPOSITIONS FOR INHIBITING CLONAL HEMATOPOIESIS THE JACKSON LABORATORY (US) 2026-03-05 US claimed
EP-4376952-A1 ANTI-SIRP-ALPHA ANTIBODIES AND METHODS OF USE THEREOF Alector LLC (US) 2024-06-05 EP claimed
CN-112863070-B Monitoring system and monitoring method of intelligent tool cabinet 江苏未来智慧信息科技有限公司 2024-03-29 CN claimed
WO-2024041228-A1 FEED LIQUID FOR PRODUCTION OF POLYSIALIC ACID, AND PREPARATION METHOD FOR POLYSIALIC ACID 山东合成远景生物科技有限公司 2024-02-29 WO claimed
CN-117106152-A Solvent-free waterproof moisture-permeable double-component polyurethane composition and preparation method and application thereof 广州贵福爵科技有限公司 2023-11-24 CN claimed
CN-111733092-B Method for producing polysialic acid by fermentation and extraction and refining method thereof 中科鸿基生物科技有限公司 2023-10-31 CN claimed
WO-2023010076-A1 ANTI-SIRP-ALPHA ANTIBODIES AND METHODS OF USE THEREOF ALECTOR LLC (US) 2023-02-02 WO claimed
CN-115125278-B Feed supplement liquid for producing polysialic acid and preparation method of polysialic acid 山东合成远景生物科技有限公司 2022-11-18 CN claimed
CN-115125278-A Feed supplement liquid for producing polysialic acid and preparation method of polysialic acid 山东合成远景生物科技有限公司 2022-09-30 CN claimed
CN-114805159-A Synthetic process of paricalcitol 正大制药(青岛)有限公司 2022-07-29 CN claimed
CN-122012005-A Bi-component polyurethane adhesive and preparation method and application thereof 江苏长能节能新材料科技有限公司 2026-05-12 CN disclosed
US-12624290-B2 Method for reducing white flicker MERCK PATENT GMBH (DE) 2026-05-12 US disclosed
EP-4021661-B1 HOT-CURING MOULD MATERIAL FOR PRODUCING CORES AND MOULDS IN THE SAND CASTING PROCESS BINDUR GMBH (DE) 2026-05-06 EP disclosed
US-12618007-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2026-05-05 US disclosed
US-20260116912-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SAGE THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-20220112426-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-04-14 US disclosed
US-20220110950-A1 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF SAGE THERAPEUTICS, INC. 2022-04-14 US disclosed
US-11261211-B2 19-NOR neuroactive steroids and methods of use thereof SAGE THERAPEUTICS, INC. (US) 2022-03-01 US disclosed
CN-114106280-A Aliphatic polyurethane resin and preparation method and application thereof 上海华峰新材料研发科技有限公司 2022-03-01 CN disclosed
US-11254872-B2 Liquid crystal media comprising polymerisable compounds MERCK PATENT GMBH (DE) 2022-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060991-A1 METHODS AND COMPOSITIONS FOR INHIBITING CLONAL HEMATOPOIESIS MCL1, TSG101, DNMT3A TAAR1 4670/4885SLC6A4 4862/4885SLC6A2 4640/4885
US-12618007-B2 Liquid-crystalline medium SOST, NES, VIM TAAR1 2081/4885SLC6A4 511/4885SLC6A2 214/4885
US-20220110950-A1 19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF NR3C2, NR3C1, CYP11B1 TAAR1 140/4885SLC6A4 226/4885SLC6A2 585/4885
US-20260116912-A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF SCN4A, CHRNA4, CACNG4 TAAR1 269/4885SLC6A4 4/4885SLC6A2 39/4885
US-12624290-B2 Method for reducing white flicker HCN4, HCN2, HCN3 TAAR1 2177/4885SLC6A4 2078/4885SLC6A2 1307/4885
US-11261211-B2 19-NOR neuroactive steroids and methods of use thereof NR3C2, HSD3B1, NR3C1 TAAR1 127/4885SLC6A4 135/4885SLC6A2 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.