Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22058789 | 0.88 | POLH (0.58) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL22549001 | 0.80 | POLH (0.74) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL28041625 | 0.79 | POLH (0.76) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL24092242 | 0.76 | POLH (0.70) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL17620267 | 0.74 | POLH (0.78) | POLHKDM4EGAAPOLBMAPT | |
| Quercetin SCHEMBL20483106 | 0.74 | MEN1 (0.79) | POLHKDM4EGAAPOLBMAPT | |
| 3-O-Methylquercetin SCHEMBL380558 | 0.74 | POLH (1.00) | POLHKDM4EGAAPOLBMAPT | |
| 3-O-Methylquercetin SCHEMBL29897544 | 0.74 | POLH (1.00) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL14786208 | 0.73 | POLH (0.81) | POLHKDM4EGAAPOLBMAPT | |
| SCHEMBL10728956 | 0.73 | POLH (1.00) | POLHKDM4EGAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4205756-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ABELIOPHYLLUM DISTICHUM EXTRACT AS ACTIVE INGREDIENT FOR TREATING ANDROGEN RECEPTOR-RELATED DISEASE | Konkuk University Glocal Industry-Academic Collaboration Foundation (KR) | 2023-07-05 | — | — | EP | disclosed |