Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.37 |
| ▸ | IL1B | P01584 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25856428 | 0.87 | NLRP3 (0.36) | NLRP3IL1BTNF | |
| SCHEMBL25856432 | 0.84 | NLRP3 (0.38) | NLRP3IL1BTNF | |
| SCHEMBL25519380 | 0.84 | NLRP3 (0.50) | NLRP3IL1B | |
| SCHEMBL25857850 | 0.81 | NLRP3 (0.42) | NLRP3IL1BEGLN1TNF | |
| SCHEMBL25856433 | 0.75 | KDM4E (0.41) | — | |
| SCHEMBL31314226 | 0.75 | EGLN1 (0.32) | NLRP3EGLN1 | |
| SCHEMBL26773007 | 0.74 | TRPA1 (0.44) | IL1BTSHR | |
| SCHEMBL31495989 | 0.72 | NLRP3 (0.39) | NLRP3IL1BEGLN1TNF | |
| SCHEMBL25858493 | 0.72 | BACE1 (0.33) | NLRP3BACE1 | |
| SCHEMBL25519495 | 0.72 | EGLN2 (0.46) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |