Sugi Predict

Sugi Predict / Compounds / SCHEMBL2585957

SCHEMBL2585957

SCHEMBL2585957

Brc1ccc(-c2nc3c4ccccc4c4ccccc4c3n2-c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DHFR P00374 2/20 0.50
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ RXFP1 Q9HBX9 2/20 0.48
▸ MAPT P10636 2/20 0.46
▸ GAA P10253 3/20 0.43
▸ ALDH1A1 P00352 6/20 0.42
▸ LMNA P02545 2/20 0.42
▸ GRM1 Q13255 1/20 0.40
▸ PI4KA P42356 1/20 0.40
▸ PI4K2B Q8TCG2 1/20 0.40
▸ PI4K2A Q9BTU6 1/20 0.40
▸ PI4KB Q9UBF8 1/20 0.40
▸ CYP2C19 P33261 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2D6 P10635 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ TSHR P16473 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697348 1.00 DHFR (0.50) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL19786204 0.94 DHFR (0.44) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL28576110 0.92 GAA (0.44) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL2585614 0.91 MEN1 (0.46) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL30507756 0.91 MEN1 (0.46) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL19013468 0.91 ALDH1A1 (0.46) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL2586996 0.90 MAPT (0.52) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL2631757 0.89 MEN1 (0.48) DHFRMEN1KMT2AMAPTGAA
SCHEMBL19013006 0.88 DHFR (0.44) DHFRMEN1KMT2ARXFP1MAPT
SCHEMBL19012889 0.88 DHFR (0.44) DHFRMEN1KMT2ARXFP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214254-B Hole-transport-type main body material, preparation method thereof and application thereof in preparation of organic electroluminescent device 华南理工大学 2022-07-26 — — CN disclosed
CN-113214286-A Green light compound based on dibenzophenazine, preparation method and device thereof 冯旗 2021-08-06 — — CN disclosed
CN-113214254-A Hole-transport-type main body material, preparation method thereof and application thereof in preparation of organic electroluminescent device 华南理工大学 2021-08-06 — — CN disclosed
CN-106661024-B Organic light-emitting compound and organic electroluminescent element using same 索路思高新材料有限公司 2021-04-20 — — CN disclosed
US-9353065-B2 Heterocyclic bridged biphenyls BASF SE (DE) 2016-05-31 — — US disclosed
US-9353065-B2 Heterocyclic bridged biphenyls BASF SE (DE) 2016-05-31 — — US disclosed
US-9240557-B2 Amine derivative, organic electroluminescence material, and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-19 — — US disclosed
US-9240557-B2 Amine derivative, organic electroluminescence material, and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-19 — — US disclosed
EP-2125752-B1 HETEROCYCLIC BRIDGED BIPHENYLS BASF SE (DE) 2015-08-12 — — EP disclosed
CN-104003950-A Organic electroluminescence phosphorescence host material, preparation method thereof and organic electroluminescence device OCEANS KING LIGHTING SCIENCE 2014-08-27 — — CN disclosed
US-20140151661-A1 AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENCE MATERIAL, AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-06-05 — — US disclosed
US-20140151661-A1 AMINE DERIVATIVE, ORGANIC ELECTROLUMINESCENCE MATERIAL, AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-06-05 — — US disclosed
CN-103772361-A Organic semiconductor material containing carbazole, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-05-07 — — CN disclosed
US-8048542-B2 Bis-phenanthroimidazolyl compound and electroluminescent device using the same NATIONAL TSING HUA UNIVERSITY (TW) 2011-11-01 — — US disclosed
US-20100253208-A1 BIS-PHENANTHROIMIDAZOLYL COMPOUND AND ELECTROLUMINESCENT DEVICE USING THE SAME E-RAY OPTOELECTRONICS TECHNOLOGY CO., LTD. (TW) 2010-10-07 — — US disclosed
WO-2010063609-A2 HOLE INJECTION MATERIAL BASF SE (DE) 2010-06-10 — — WO disclosed
US-20100109514-A1 HETEROCYCLIC BRIDGED BIPHENYLS UDC IRELAND LIMITED (IE) 2010-05-06 — — US disclosed
US-20100109514-A1 HETEROCYCLIC BRIDGED BIPHENYLS UDC IRELAND LIMITED (IE) 2010-05-06 — — US disclosed
WO-2008119666-A1 HETEROCYCLIC BRIDGED BIPHENYLS BASF SE (CH) 2008-10-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100109514-A1 HETEROCYCLIC BRIDGED BIPHENYLS OCIAD1, SBDS, OCIAD2 DHFR 433/4885MEN1 3281/4885KMT2A 3605/4885
US-20100253208-A1 BIS-PHENANTHROIMIDAZOLYL COMPOUND AND ELECTROLUMINESCENT DEVICE USING THE SAME SLC43A3, SLC29A1, SLC29A2 DHFR 3070/4885MEN1 2505/4885KMT2A 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.