Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25861928 | 0.81 | TRPA1 (0.36) | NLRP3TRPA1ESR1ESR2 | |
| SCHEMBL25854967 | 0.79 | IL1B (0.47) | NLRP3 | |
| SCHEMBL25863121 | 0.78 | NLRP3 (0.34) | NLRP3 | |
| SCHEMBL25864075 | 0.77 | IL1B (0.37) | NLRP3TRPA1 | |
| SCHEMBL25861616 | 0.76 | NLRP3 (0.39) | NLRP3HSD17B10 | |
| SCHEMBL25857462 | 0.76 | NLRP3 (0.62) | NLRP3 | |
| SCHEMBL30488480 | 0.75 | IL1B (0.52) | NLRP3 | |
| SCHEMBL29030548 | 0.75 | IL1B (0.52) | NLRP3 | |
| SCHEMBL25856248 | 0.75 | IL1B (0.52) | NLRP3 | |
| SCHEMBL25858995 | 0.75 | NLRP3 (0.38) | NLRP3HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |