Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25861616 | 0.85 | NLRP3 (0.39) | NLRP3HSD17B10 | |
| SCHEMBL25857850 | 0.77 | NLRP3 (0.42) | NLRP3EGLN1 | |
| SCHEMBL25856264 | 0.76 | IL1B (0.51) | NLRP3 | |
| SCHEMBL25857462 | 0.75 | NLRP3 (0.62) | NLRP3 | |
| SCHEMBL25861920 | 0.75 | NLRP3 (0.39) | NLRP3HSD17B10 | |
| SCHEMBL25858838 | 0.73 | ALDH1A1 (0.45) | NLRP3CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL25859518 | 0.71 | NLRP3 (0.37) | NLRP3EGLN1 | |
| SCHEMBL25858377 | 0.70 | NLRP3 (0.35) | NLRP3 | |
| SCHEMBL25860307 | 0.69 | EGFR (0.31) | — | |
| SCHEMBL25860146 | 0.69 | NLRP3 (0.31) | NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131277-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USES THEREOF | 药捷安康(南京)科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |