Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21166950 | 0.88 | KDM4E (0.33) | KDM4EALDH1A1HPGD | |
| SCHEMBL19478317 | 0.79 | CA2 (0.39) | — | |
| SCHEMBL11577916 | 0.73 | CA2 (0.42) | KDM4EALDH1A1HPGD | |
| SCHEMBL7107814 | 0.73 | IGF1R (0.31) | — | |
| SCHEMBL24418066 | 0.71 | CA2 (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL14708745 | 0.71 | CA12 (0.32) | — | |
| SCHEMBL19478141 | 0.69 | MAPK1 (0.42) | ALDH1A1HPGD | |
| SCHEMBL1785291 | 0.68 | — | — | |
| SCHEMBL164556 | 0.66 | — | — | |
| SCHEMBL24725043 | 0.66 | ADRA1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234922-A1 | PROCESSES FOR THE PREPARATION OF 4,6,7-TRIFLUORO-1H-INDOLE-2-CARBOXYLIC ACID | ENANTA PHARMACEUTICALS, INC. | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234922-A1 | PROCESSES FOR THE PREPARATION OF 4,6,7-TRIFLUORO-1H-INDOLE-2-CARBOXYLIC ACID | ACE2, HTR3C, SARS1 | KDM4E 793/4885ALDH1A1 1129/4885HPGD 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.