SCHEMBL19478317

SCHEMBL19478317

COCc1c(F)c(F)c(CO)c(Br)c1F

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
GCGR P47871 1/20 0.35
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL359266 0.85 GCGR (0.39) CA2CA4GCGR
SCHEMBL21166950 0.81 KDM4E (0.33) CA2CA4
SCHEMBL25864217 0.79 KDM4E (0.33)
SCHEMBL19688655 0.78 GCGR (0.36) GCGR
SCHEMBL29843338 0.78 GCGR (0.36) GCGR
SCHEMBL7107814 0.78 IGF1R (0.31) GCGR
SCHEMBL9766074 0.76 CA2 (0.39) CA2CA4GCGR
Acetic Acid SCHEMBL22129233 0.76 PRKCE (0.36) GCGR
SCHEMBL19478240 0.76 GCGR (0.35) GCGR
SCHEMBL25300101 0.75 DRD4 (0.40) CA2CA4DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017179568-A1 ESTER COMPOUND AND USE THEREOF 大日本除蟲菊株式会社 2017-10-19 WO disclosed