SCHEMBL9355307

SCHEMBL9355307

N#COc1ccc(S(=O)(=O)c2ccc(OC#N)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.52
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
GAA P10253 4/20 0.44
ALDH1A1 P00352 4/20 0.42
HTT P42858 3/20 0.41
ELANE P08246 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 2/20 0.41
LMNA P02545 2/20 0.41
HTR6 P50406 2/20 0.41
MAPK1 P28482 1/20 0.41
MPO P05164 1/20 0.41
CYP2C9 P11712 1/20 0.41
TSHR P16473 1/20 0.41
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185192 1.00 PKM (0.52) PKMPOLBMAPTGAAALDH1A1
SCHEMBL2591090 0.94 SMN1; SMN2 (0.50) PKMPOLBMAPTGAAALDH1A1
SCHEMBL9818321 0.92 HTR6 (0.54) PKMPOLBMAPTGAAALDH1A1
SCHEMBL11706979 0.90 PKM (0.59) PKMPOLBMAPTGAAALDH1A1
SCHEMBL2587780 0.86 HSD11B1 (0.44) PKMPOLBMAPTGAAALDH1A1
SCHEMBL17576538 0.84 PKM (0.39) PKMPOLBMAPTGAAALDH1A1
SCHEMBL8396902 0.83 MGLL (0.49) PKMALDH1A1HTTLMNAMAPK1
SCHEMBL12212858 0.83 LMNA (0.46) PKMPOLBMAPTGAAALDH1A1
SCHEMBL19757307 0.83 ENPP2 (0.45) PKM
SCHEMBL2586433 0.82 HTT (0.44) PKMPOLBMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344676-B1 CYANATE ESTER DUAL CURE RESINS FOR ADDITIVE MANUFACTURING CARBON INC (US) 2023-04-12 EP claimed
EP-0407176-B1 Process for producing a cured cyanate ester resin product MITSUBISHI GAS CHEMICAL CO (JP) 1994-11-02 EP claimed
WO-2024213237-A1 CURABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2024-10-17 WO disclosed
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 EP disclosed
EP-4153658-B1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2023-12-06 EP disclosed
EP-4153658-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2023-03-29 EP disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 WO disclosed
EP-0321412-B1 Di- or polycyanate compounds, substituted bicyclo[2.2.1]5 heptene-dicarbon imides, blends containing thermoplastics, and their use CIBA-GEIGY AG (CH) 1993-09-08 EP disclosed
EP-0265374-B1 Mixtures containing di- or polycyanate compounds and substituted bicyclo [2.2.1]hept-5-ene-2,3-dicarboxylic imides, and their use CIBA-GEIGY AG (CH) 1990-12-19 EP disclosed
EP-0321412-A2 Di- or polycyanate compounds, substituted bicyclo[2.2.1]5 heptene-dicarbon imides, blends containing thermoplastics, and their use CIBA-GEIGY AG (CH) 1989-06-21 EP disclosed
EP-0265374-A2 Mixtures containing di- or polycyanate compounds and substituted bicyclo [2.2.1]hept-5-ene-2,3-dicarboxylic imides, and their use CIBA-GEIGY AG (CH) 1988-04-27 EP disclosed