SCHEMBL2587780

SCHEMBL2587780

CC(C)(c1ccc(OC#N)cc1)c1ccc(S(=O)(=O)c2ccc(C(C)(C)c3ccc(OC#N)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.44
PKM P14618 3/20 0.44
ELANE P08246 2/20 0.44
MAPT P10636 3/20 0.40
POLB P06746 1/20 0.40
NR3C2 P08235 1/20 0.39
GAA P10253 2/20 0.39
ALDH1A1 P00352 4/20 0.37
HPGD P15428 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
GMNN O75496 1/20 0.37
LMNA P02545 1/20 0.37
DRD1 P21728 1/20 0.37
DRD3 P35462 1/20 0.37
CCR2 P41597 1/20 0.37
RAB9A P51151 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2586433 0.95 HTT (0.44) HSD11B1PKMELANEMAPTPOLB
SCHEMBL25961 0.86 HPGD (0.41) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL1555244 0.86 HPGD (0.41) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL9355307 0.86 PKM (0.52) PKMELANEMAPTPOLBGAA
SCHEMBL7789786 0.86 HPGD (0.41) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL185192 0.86 PKM (0.52) PKMELANEMAPTPOLBGAA
SCHEMBL22966364 0.80 KIF11 (0.42) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL20547222 0.80 KIF11 (0.42) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL22966431 0.80 KIF11 (0.42) MAPTPOLBALDH1A1HPGDSMN1; SMN2
SCHEMBL2580928 0.80 HPGD (0.42) ELANEMAPTPOLBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664341-B2 Vinylbenzyl ethers of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES, LLC (US) 2014-03-04 US disclosed
US-8519066-B2 Poly(allyl ethers) of polycyclopentadiene polyphenol DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-27 US disclosed
US-20130211015-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-15 US disclosed
EP-2563756-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
EP-2563755-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL Dow Global Technologies LLC (US) 2013-03-06 EP disclosed
US-20130041114-A1 POLY(ALLYL ETHERS) OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2013-02-14 US disclosed
WO-2011136847-A1 POLY(ALLYL ETHER)S OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
WO-2011136845-A1 VINYLBENZYL ETHERS OF POLYCYCLOPENTADIENE POLYPHENOL DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-03 WO disclosed
US-6337375-B1 RESIN WITH COLOR AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-01-08 US disclosed
US-6190759-B1 ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT INTERNATIONAL BUSINESS MACHINES CORPORATION 2001-02-20 US disclosed
EP-0147547-A2 Preparation of aromatic cyanates THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
EP-0147548-A2 Novel polyaromatic cyanates and polytriazines prepared therefrom THE DOW CHEMICAL COMPANY (US) 1985-07-10 EP disclosed
US-4528366-A Production of polytriazines from aromatic polycyanates with cobalt salt of a carboxylic acid as catalyst THE DOW CHEMICAL COMPANY (US) 1985-07-09 US disclosed
WO-1985002185-A1 A PROCESS FOR THE PREPARATION OF AROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
WO-1985002184-A1 POLYAROMATIC CYANATES, A PROCESS FOR PREPARING THE POLYAROMATIC CYANATES, AND POLYTRIAZINES PREPARED FROM THE POLYAROMATIC CYANATES THE DOW CHEMICAL COMPANY (US) 1985-05-23 WO disclosed
US-4195132-A CROSSLINKING BY WAT OF TRIAZINE RINGS BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4116946-A OLEFIN, CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1978-09-26 US disclosed
US-4094852-A Process for the production of polytriazines in the presence of high-boiling esters BAYER AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed
US-4066577-A HIGH MOLECULAR WEIGHT POLYTRIAZINES OF SOLUBLE POLYMERIC N-CYANO-ISOUREA ETHERS BAYER AKTIENGESELLSCHAFT (DT) 1978-01-03 US disclosed
US-4031067-A Polytriazines and a process for their production BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed