SCHEMBL25865417

SCHEMBL25865417

CNCCCCC(N)C(=O)NC(Cc1ccccc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 2/20 0.51
▸ NPY4R P50391 3/20 0.50
▸ NPY1R P25929 2/20 0.50
▸ NPY2R P49146 2/20 0.50
▸ NPY5R Q15761 2/20 0.50
▸ FCER2 P06734 2/20 0.48
▸ MMP1 P03956 2/20 0.48
▸ CTSL P07711 1/20 0.47
▸ MMP2 P08253 1/20 0.47
▸ ERAP2 Q6P179 3/20 0.47
▸ ERAP1 Q9NZ08 3/20 0.47
▸ LNPEP Q9UIQ6 2/20 0.47
▸ IL1RN P18510 1/20 0.47
▸ KISS1R Q969F8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21135937 0.88 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RFCER2
SCHEMBL21135676 0.88 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RFCER2
SCHEMBL19891256 0.88 MMP2 (0.55) MMP1MMP2
SCHEMBL26211997 0.87 NPY4R (0.48) NPY4RNPY1RNPY2RNPY5RFCER2
SCHEMBL23223538 0.86 MMP2 (0.63) FCER2MMP1CTSLMMP2ERAP2
SCHEMBL30534073 0.86 MMP2 (0.63) FCER2MMP1CTSLMMP2ERAP2
SCHEMBL23223604 0.86 MMP2 (0.63) FCER2MMP1CTSLMMP2ERAP2
SCHEMBL16862448 0.86 MMP2 (0.63) FCER2MMP1CTSLMMP2ERAP2
SCHEMBL18333007 0.83 HDAC3 (0.58) FCER2MMP1CTSLERAP2ERAP1
SCHEMBL23680153 0.82 REN (0.53) NPY4RNPY1RNPY2RNPY5RMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES PITRM1, NME4, PDF OPRK1 2216/4885NPY4R 822/4885NPY1R 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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