SCHEMBL25865436

SCHEMBL25865436

COCCOCCOCCOCCOCCOCCOCCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@H](N)CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.58
NPY1R P25929 9/20 0.57
NPY5R Q15761 7/20 0.57
NPY2R P49146 5/20 0.57
OPRM1 P35372 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24147031 0.92 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL25867398 0.92 CCKBR (0.48) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL18258324 0.91 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL25866171 0.91 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL24146579 0.91 NPY4R (0.54) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL24146766 0.90 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL24146761 0.89 NPY4R (0.52) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL24147032 0.89 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL26179135 0.88 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL25308138 0.87 NPY4R (0.51) NPY4RNPY1RNPY5RNPY2ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
EP-4168424-A1 PRODRUGS OF MITOCHODRIA-TARGETING OLIGOPEPTIDES Stealth BioTherapeutics Inc. (US) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES PITRM1, NME4, PDF NPY4R 822/4885NPY1R 1075/4885NPY5R 2560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.