SCHEMBL25867398

SCHEMBL25867398

COCCOCCOCCOCCOCCOCCOCCOC(=O)NCCCC[C@H](NC(=O)[C@H](Cc1c(C)cc(O)cc1C)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 4/20 0.48
NPY4R P50391 9/20 0.48
NPY1R P25929 6/20 0.46
NPY2R P49146 5/20 0.46
NPY5R Q15761 5/20 0.46
REN P00797 1/20 0.46
OPRM1 P35372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24147041 0.93 NPY4R (0.48) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL25865436 0.92 NPY4R (0.58) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL25867315 0.91 CCKBR (0.50) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL19862399 0.91 NPY4R (0.52) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL19862098 0.91 NPY4R (0.52) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL18048887 0.91 NPY4R (0.52) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL19862397 0.91 NPY4R (0.52) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL19862401 0.91 NPY4R (0.53) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL24147042 0.90 NPY4R (0.51) CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL25867236 0.88 NPY4R (0.49) CCKBRNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-07-20 US disclosed
EP-4168424-A1 PRODRUGS OF MITOCHODRIA-TARGETING OLIGOPEPTIDES Stealth BioTherapeutics Inc. (US) 2023-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227499-A1 PRODRUGS OF MITOCHONDRIA-TARGETING OLIGOPEPTIDES PITRM1, NME4, PDF CCKBR 1024/4885NPY4R 822/4885NPY1R 1075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.