SCHEMBL25865687

SCHEMBL25865687

CC(C)(C)[Si](C)(C)OC(CNCO)c1ccncc1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23354885 0.81 ADRB2 (0.39) ADRB2ADRB1ADRB3
SCHEMBL29873480 0.78 PCSK9 (0.41) ADRB2ADRB1ADRB3CYP3A4
SCHEMBL9178986 0.77 KDM4E (0.39) CA2
SCHEMBL23354701 0.77 CA2 (0.35) ADRB2ADRB1ADRB3CYP3A4CYP2C19
SCHEMBL1677942 0.75 CA2 (0.39) CYP3A4CYP2C19CA2
SCHEMBL23354728 0.71 CNR1 (0.36) CYP3A4CA2
SCHEMBL5572477 0.71 CA2 (0.32) CA2
SCHEMBL9563493 0.70 TAAR1 (0.43) CYP3A4CYP2C19
SCHEMBL9563491 0.70 TAAR1 (0.43) CYP3A4CYP2C19
SCHEMBL9602856 0.70 CYP3A4 (0.36) CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126006-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2023-07-06 WO disclosed