Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CASP7 | P55210 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514651 | 0.77 | PDE4A (0.60) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL25306709 | 0.73 | ALDH1A1 (0.48) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13477776 | 0.71 | PDE4A (0.53) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL10026171 | 0.70 | PDE4A (0.51) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL13955872 | 0.70 | PDE4A (0.60) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL27915929 | 0.69 | PDE4A (0.59) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL10688020 | 0.68 | TDP2 (0.54) | PDE4AKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL8840880 | 0.68 | PDE4A (0.67) | PDE4AKDM4EMEN1KMT2AMAPT | |
| SCHEMBL3125629 | 0.67 | PDE4A (0.72) | PDE4AABCG2ABCB1KDM4EMEN1 | |
| SCHEMBL14011591 | 0.67 | ABCG2 (0.77) | ABCG2ABCB1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137453-A1 | PRODRUGS OF 3,4-METHYLENEDIOXY-N-METHCATHINONE AND USES THEREOF | TERRAN BIOSCIENCES INC. (US) | 2023-07-20 | — | — | WO | disclosed |