Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | PGK2 | P07205 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28467648 | 0.87 | GABBR2 (0.44) | GABBR2GABBR1NFE2L2ALDH1A1TRPA1 | |
| SCHEMBL6554663 | 0.87 | GABBR2 (0.44) | GABBR2GABBR1NFE2L2ALDH1A1TRPA1 | |
| SCHEMBL3717943 | 0.87 | GABBR2 (0.44) | GABBR2GABBR1NFE2L2ALDH1A1TRPA1 | |
| SCHEMBL8011123 | 0.84 | GABBR2 (0.51) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL8011119 | 0.84 | GABBR2 (0.51) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL2474610 | 0.81 | NFE2L2 (0.41) | NFE2L2RAPGEF4NOTUMPGK1PGK2 | |
| SCHEMBL6441622 | 0.80 | GABBR2 (0.48) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL6441626 | 0.80 | GABBR2 (0.48) | GABBR2GABBR1ALDH1A1TRPA1LMNA | |
| SCHEMBL21399871 | 0.79 | NFE2L2 (0.43) | NFE2L2RAPGEF4NOTUMPGK1PGK2 | |
| SCHEMBL19166263 | 0.79 | NFE2L2 (0.43) | NFE2L2RAPGEF4NOTUMPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220427-A1 | PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS | CORTEVA AGRISCIENCE LLC (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220427-A1 | PROCESSES RELATED TO FORMATION OF ARYLCYCLOPROPYL CARBOXYLIC ACIDS | DDT, PCCA, DDC | GABBR2 888/4885GABBR1 635/4885NFE2L2 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.