Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876576 | 0.84 | CYP3A4 (0.43) | MEN1KMT2ACYP3A4HSD17B10CYP2D6 | |
| SCHEMBL25870687 | 0.76 | CYP3A4 (0.41) | MEN1KMT2ACYP3A4HSD17B10CYP2D6 | |
| SCHEMBL25876321 | 0.76 | CYP3A4 (0.43) | MEN1KMT2ACYP3A4HSD17B10CYP2D6 | |
| SCHEMBL25870685 | 0.75 | HIF1A (0.39) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL25870686 | 0.74 | CYP3A4 (0.44) | MEN1KMT2ACYP3A4HSD17B10CYP2D6 | |
| SCHEMBL25870426 | 0.73 | CYP2D6 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL12308626 | 0.71 | CYP1A2 (0.37) | CYP3A4CYP2D6CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL12308622 | 0.68 | CYP1A2 (0.43) | CYP2D6CYP1A2 | |
| SCHEMBL25870419 | 0.67 | CYP3A4 (0.45) | MEN1KMT2ACYP3A4HSD17B10CYP2D6 | |
| SCHEMBL12308617 | 0.66 | RIPK1 (0.36) | MEN1KMT2ACYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |