Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876576 | 0.84 | CYP3A4 (0.43) | HIF1ACYP3A4MEN1CYP2C19KMT2A | |
| SCHEMBL25870428 | 0.75 | MEN1 (0.44) | CYP3A4MEN1MAPK1CYP2C19KMT2A | |
| SCHEMBL25870686 | 0.74 | CYP3A4 (0.44) | HIF1ACYP3A4MEN1MAPK1CYP2C19 | |
| SCHEMBL25870581 | 0.74 | MEN1 (0.43) | CYP3A4MEN1CYP2C19KMT2ACYP2C9 | |
| SCHEMBL25870426 | 0.70 | CYP2D6 (0.39) | CYP3A4MAPK1CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL25870687 | 0.68 | CYP3A4 (0.41) | HIF1ACYP3A4MEN1MAPK1CYP2C19 | |
| SCHEMBL25876321 | 0.67 | CYP3A4 (0.43) | HIF1ACYP3A4MEN1MAPK1CYP2C19 | |
| SCHEMBL12308626 | 0.67 | CYP1A2 (0.37) | CYP3A4MAPK1CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL30984699 | 0.66 | CYP11B2 (0.53) | HIF1ACYP3A4MEN1MAPK1CYP2C19 | |
| SCHEMBL12308617 | 0.66 | RIPK1 (0.36) | CYP3A4MEN1CYP2C19KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |