Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870687 | 0.92 | CYP3A4 (0.41) | CYP3A4MEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL25870686 | 0.85 | CYP3A4 (0.44) | CYP3A4MEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL25870419 | 0.81 | CYP3A4 (0.45) | CYP3A4MEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL25870421 | 0.77 | ITGB3 (0.39) | CYP3A4MEN1KMT2AACACBALDH1A1 | |
| SCHEMBL25876576 | 0.76 | CYP3A4 (0.43) | CYP3A4MEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL25870428 | 0.76 | MEN1 (0.44) | CYP3A4MEN1KMT2AHSD17B10CYP2D6 | |
| SCHEMBL25870685 | 0.67 | HIF1A (0.39) | CYP3A4MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL25589849 | 0.66 | HRH4 (0.48) | MEN1KMT2AHSD17B10CYP1A2USP2 | |
| SCHEMBL12723192 | 0.65 | CYP3A4 (0.48) | CYP3A4MEN1KMT2ACYP2C9MAPK1 | |
| SCHEMBL24590204 | 0.65 | POLB (0.49) | CYP3A4KMT2ACYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |