Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.31 |
| ▸ | CYBB | P04839 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870678 | 0.90 | MAPT (0.40) | EP300MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18863393 | 0.88 | MAPT (0.40) | EP300CISD1MAOAMAOBMAPT | |
| SCHEMBL25870688 | 0.83 | MAPT (0.36) | EP300CISD1MAPTAPPMEN1 | |
| SCHEMBL25870735 | 0.83 | LMNA (0.39) | EP300CISD1MAOAMAOBMAPT | |
| SCHEMBL25870710 | 0.82 | MAPT (0.37) | EP300CISD1MAOAMAOBMAPT | |
| SCHEMBL28693064 | 0.81 | APP (0.30) | APP | |
| SCHEMBL25870715 | 0.79 | MAPT (0.34) | EP300CISD1MAOAMAOBMAPT | |
| SCHEMBL25870691 | 0.79 | MAPT (0.35) | EP300CISD1MAOAMAOBMAPT | |
| SCHEMBL25870746 | 0.79 | TNFRSF1A (0.44) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL25870674 | 0.77 | KMT2A (0.38) | MAPTMEN1KMT2AALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |