Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870743 | 0.87 | TNFRSF1A (0.42) | TNFRSF1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18863393 | 0.85 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL25870678 | 0.81 | MAPT (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL25870735 | 0.80 | LMNA (0.39) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL25870688 | 0.80 | MAPT (0.36) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL25870710 | 0.79 | MAPT (0.37) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL25870679 | 0.79 | EP300 (0.34) | ALDH1A1MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL25870715 | 0.78 | MAPT (0.34) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL10134151 | 0.78 | TNFRSF1A (0.49) | TNFRSF1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28693064 | 0.78 | APP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |