SCHEMBL2461744

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2459170	0.81	MAOA (0.35)	CYP11B1CYP11B2CYP1A2RAB9ANPC1
	SCHEMBL2587071	0.81	KDM4E (0.37)	RAB9ANPC1CYP3A4IDO1HRH3
	SCHEMBL2462305	0.81	KDM4E (0.39)	RAB9ANPC1CYP3A4IDO1HRH3
	SCHEMBL2581768	0.78	ALDH1A1 (0.35)	RAB9ANPC1CYP3A4IDO1HRH3
	SCHEMBL2433158	0.77	ALDH1A1 (0.39)	RAB9ANPC1CYP3A4IDO1HRH3
	SCHEMBL1135960	0.77	MAOB (0.41)	RAB9ANPC1CYP3A4HRH3CLK1
	SCHEMBL12160476	0.76	HRH3 (0.36)	RAB9ANPC1CYP3A4CYP19A1IDO1
	SCHEMBL2461065	0.76	KDM4E (0.40)	HRH3KDRKDM4EALDH1A1
	SCHEMBL2432159	0.75	NPC1 (0.37)	RAB9ANPC1CYP3A4IDO1HRH3
	SCHEMBL2432114	0.75	NPC1 (0.37)	RAB9ANPC1CYP3A4IDO1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.