SCHEMBL2581768

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2582111	0.85	HRH3 (0.35)	ALDH1A1KDM4EHSD17B10HRH3NPC1
	SCHEMBL2587071	0.85	KDM4E (0.37)	ALDH1A1KDM4EHSD17B10HPGDMAPT
	SCHEMBL2462305	0.85	KDM4E (0.39)	ALDH1A1KDM4EHSD17B10HPGDMAPT
	SCHEMBL12160476	0.81	HRH3 (0.36)	ALDH1A1KDM4EHSD17B10HRH3NPC1
	SCHEMBL2459170	0.80	MAOA (0.35)	ALDH1A1KDM4EHSD17B10MAPTHRH3
	SCHEMBL2461744	0.78	PDE2A (0.35)	ALDH1A1KDM4EHSD17B10HRH3NPC1
	SCHEMBL2432159	0.77	NPC1 (0.37)	ALDH1A1KDM4EHSD17B10MAPTHRH3
	SCHEMBL3362491	0.77	ESR1 (0.38)	ALDH1A1KDM4EHSD17B10HPGDESR1
	SCHEMBL2578644	0.77	ESR1 (0.42)	ALDH1A1KDM4EESR1ESR2RAB9A
	SCHEMBL2433158	0.77	ALDH1A1 (0.39)	ALDH1A1KDM4EHSD17B10MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.