Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863392 | 0.88 | MAPT (0.33) | TNFRSF1AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25870746 | 0.87 | TNFRSF1A (0.44) | TNFRSF1AENPP3ALDH1A1MAPTMEN1 | |
| SCHEMBL25870674 | 0.85 | KMT2A (0.38) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL18863388 | 0.83 | KDM4E (0.31) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28932832 | 0.82 | ALDH1A1 (0.31) | ALDH1A1MAPTKDM4E | |
| SCHEMBL28705799 | 0.82 | KDM4E (0.31) | ALDH1A1KDM4E | |
| SCHEMBL25870682 | 0.81 | NOX4 (0.32) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL25870726 | 0.81 | LMNA (0.34) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL18863389 | 0.81 | SIRT2 (0.50) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL25870705 | 0.80 | MAPT (0.32) | ALDH1A1MAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |