SCHEMBL25870816

SCHEMBL25870816

CC(C)c1ccc(N)c(N2CCNCC2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB1 P08588 4/20 0.41
MAPT P10636 3/20 0.41
GAA P10253 3/20 0.41
HTT P42858 3/20 0.41
HTR6 P50406 3/20 0.41
MAPK1 P28482 2/20 0.41
HTR3E A5X5Y0 2/20 0.41
HTR3B O95264 2/20 0.41
HTR3A P46098 2/20 0.41
HTR3D Q70Z44 2/20 0.41
HTR3C Q8WXA8 2/20 0.41
DRD2 P14416 1/20 0.41
CYP2C19 P33261 1/20 0.41
DRD3 P35462 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41
PTK2B Q14289 1/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25870823 0.85 GAA (0.56) MAPTGAAHTTMAPK1KDM4E
SCHEMBL25108545 0.83 GAA (0.59) MAPTGAAHTTMAPK1KDM4E
SCHEMBL22422339 0.82 ADRB1 (0.54) ADRB1HTR6HTR3EHTR3BHTR3A
SCHEMBL25870772 0.81 LGMN (0.61) MAPTGAAHTTMAPK1KDM4E
SCHEMBL20883739 0.79 ADRB1 (0.46) ADRB1MAPTHTR6HTR3EHTR3B
SCHEMBL17660600 0.79 CDK1 (0.43) ADRB1MAPTGAAHTR6HTR3E
SCHEMBL18068239 0.79 HTR3A (0.58) ADRB1HTR6HTR3EHTR3BHTR3A
SCHEMBL14924034 0.79 ADRB1 (0.51) ADRB1MAPTHTR6HTR3EHTR3B
SCHEMBL7805793 0.78 GAA (0.46) ADRB1MAPTGAAHTTHTR6
SCHEMBL20883553 0.77 ADRB1 (0.42) ADRB1MAPTHTR6MAPK1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF ADRB1 2038/4885MAPT 235/4885GAA 996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.