SCHEMBL25870823

SCHEMBL25870823

CC(C)c1ccc(N)c(N2CCCC2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.56
ALDH1A1 P00352 7/20 0.56
HTT P42858 5/20 0.56
MAPT P10636 4/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
MAPK1 P28482 2/20 0.56
S100B P04271 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
PKM P14618 1/20 0.56
ALOX15 P16050 1/20 0.56
KEAP1 Q14145 1/20 0.47
KDM4E B2RXH2 5/20 0.45
PTK2B Q14289 2/20 0.45
RECQL P46063 2/20 0.45
ALOX12 P18054 1/20 0.43
HIF1A Q16665 1/20 0.43
LGMN Q99538 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25108545 0.98 GAA (0.59) GAAALDH1A1HTTMAPTMEN1
SCHEMBL25870816 0.85 ADRB1 (0.41) GAAALDH1A1HTTMAPTMEN1
SCHEMBL25870772 0.85 LGMN (0.61) GAAALDH1A1HTTMAPTMEN1
SCHEMBL12074844 0.80 LMNA (0.52) GAAALDH1A1HTTMAPTMEN1
SCHEMBL12160692 0.79 ALDH1A1 (0.43) GAAALDH1A1HTTMAPTMEN1
SCHEMBL20351350 0.79 ALDH1A1 (0.44) GAAALDH1A1HTTMAPTMEN1
SCHEMBL12075014 0.77 LMNA (0.42) GAAALDH1A1HTTMAPTMEN1
SCHEMBL12160700 0.76 ALDH1A1 (0.53) GAAALDH1A1HTTMAPTMEN1
SCHEMBL12515693 0.76 LMNA (0.51) GAAALDH1A1HTTMAPTLMNA
SCHEMBL1339913 0.76 MAPT (0.61) GAAALDH1A1HTTMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND AUTOTAC INC. (KR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174470-A1 COMPOUND AS A UBR BOX DOMAIN LIGAND UBR4, UBQLN2, UBTF GAA 996/4885ALDH1A1 2317/4885HTT 258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.