Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204588 | 0.84 | POLB (0.53) | CYP11B1CYP11B2POLBSMN1; SMN2LMNA | |
| SCHEMBL9883961 | 0.82 | CYP11B1 (0.44) | CYP11B1CYP11B2POLBSMN1; SMN2LMNA | |
| SCHEMBL13782270 | 0.78 | CYP11B1 (0.46) | CYP11B1CYP11B2POLBSMN1; SMN2LMNA | |
| SCHEMBL1023745 | 0.76 | TDP1 (0.70) | CYP11B1CYP11B2SMN1; SMN2LMNAMAPT | |
| SCHEMBL9883726 | 0.74 | CYP11B1 (0.43) | CYP11B1CYP11B2POLBSMN1; SMN2LMNA | |
| SCHEMBL4724897 | 0.72 | DPP4 (0.50) | CYP11B1CYP11B2POLBSMN1; SMN2LMNA | |
| SCHEMBL3042764 | 0.72 | PTGS2 (0.48) | CYP11B1CYP11B2SMN1; SMN2HTT | |
| SCHEMBL18762215 | 0.71 | MEN1 (0.41) | CYP11B1CYP11B2SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL14733932 | 0.71 | POLB (0.71) | POLBLMNAMAPTHTTTDP1 | |
| SCHEMBL9450146 | 0.71 | TDP1 (0.62) | CYP11B1CYP11B2SMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226096-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | RTCB, HNRNPA1, HNRNPAB | CYP11B1 4289/4885CYP11B2 4589/4885POLB 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.