Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13782270 | 0.86 | CYP11B1 (0.46) | CYP11B1CYP11B2TLR8TDP1ADORA2A | |
| SCHEMBL25870842 | 0.82 | CYP11B1 (0.41) | CYP11B1CYP11B2TDP1LMNASMN1; SMN2 | |
| SCHEMBL8204588 | 0.78 | POLB (0.53) | CYP11B1CYP11B2TDP1ADORA2ALMNA | |
| SCHEMBL9883726 | 0.78 | CYP11B1 (0.43) | CYP11B1CYP11B2TDP1LMNASMN1; SMN2 | |
| SCHEMBL4724897 | 0.76 | DPP4 (0.50) | CYP11B1CYP11B2TLR8ADORA2ALMNA | |
| SCHEMBL3042764 | 0.76 | PTGS2 (0.48) | CYP11B1CYP11B2SMN1; SMN2HTTADORA2B | |
| SCHEMBL12985518 | 0.74 | ALDH1A1 (0.42) | CYP11B1CYP11B2SMN1; SMN2HTTMAPT | |
| SCHEMBL230330 | 0.73 | TDP1 (0.78) | CYP11B1CYP11B2TDP1LMNASMN1; SMN2 | |
| SCHEMBL19848066 | 0.72 | TLR8 (0.43) | CYP11B1CYP11B2TLR8TDP1ADORA2A | |
| Bromide SCHEMBL10912945 | 0.71 | TDP1 (0.75) | CYP11B1CYP11B2TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193214-B2 | Chymase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-05 | — | — | US | disclosed |
| US-20100029637-A1 | Chymase Inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029637-A1 | Chymase Inhibitors | CMA1, CPA3, SERPINB1 | CYP11B1 3065/4885CYP11B2 3119/4885TLR8 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.