Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.80 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.80 |
| ▸ | CNR2 | P34972 | 1/20 | 0.80 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | PTGES | O14684 | 1/20 | 0.65 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448804 | 0.93 | AKR1C3 (0.83) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL20259423 | 0.90 | PTGS2 (0.78) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL20346373 | 0.90 | PTGS2 (0.79) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL30426824 | 0.89 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL14086813 | 0.89 | PTGS2 (1.00) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL17369560 | 0.88 | PTGS2 (0.64) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL10549590 | 0.87 | PTGS2 (0.80) | PTGS2AKR1C3AKR1C2LMNAPTGS1 | |
| SCHEMBL17369544 | 0.87 | PTGS2 (0.66) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL17945899 | 0.87 | PTGS2 (0.66) | PTGS2AKR1C3CNR2AKR1C2LMNA | |
| SCHEMBL27768669 | 0.85 | AKR1C3 (0.78) | PTGS2AKR1C3CNR2AKR1C2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227425-A1 | REAGENTS AND PROCESS FOR DIRECT C-H FUNCTIONALIZATION | CFH, DOHH, CTSH | PTGS2 3723/4885AKR1C3 598/4885CNR2 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.