Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916395 | 0.87 | PLAU (0.52) | DYRK1AHASPINRAB9ACYP1A2CYP2A6 | |
| SCHEMBL23457925 | 0.81 | KRAS (0.49) | DYRK1ATRPA1RAB9ACYP1A2CYP2A6 | |
| SCHEMBL20609543 | 0.78 | ACHE (0.62) | TRPA1RAB9ACYP1A2PDE3BPDE3A | |
| SCHEMBL13385161 | 0.78 | TRPA1 (0.56) | DYRK1ATRPA1RAB9ACYP1A2RIOK2 | |
| SCHEMBL10024935 | 0.77 | LMNA (0.41) | DYRK1ATRPA1RAB9ACYP2A6PLAU | |
| SCHEMBL23877038 | 0.77 | CYP2A6 (0.41) | RAB9ACYP1A2CYP2A6CCR1CCR5 | |
| SCHEMBL6389633 | 0.77 | TRPA1 (0.62) | DYRK1ATRPA1HASPINRAB9ACYP1A2 | |
| SCHEMBL3266115 | 0.77 | DYRK1A (0.54) | DYRK1ATRPA1HASPINRAB9ACYP1A2 | |
| SCHEMBL23877296 | 0.77 | L3MBTL1 (0.46) | DYRK1AHASPINRAB9ACYP1A2CYP2A6 | |
| SCHEMBL28822473 | 0.76 | CASR (0.50) | TRPA1RAB9ARIOK2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707471-B2 | ENPP1 inhibitors and their use for the treatment of cancer | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707471-B2 | ENPP1 inhibitors and their use for the treatment of cancer | ENPP1, ENPP3, ENTPD1 | DYRK1A 2887/4885TRPA1 4835/4885HASPIN 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.