SCHEMBL25875489

SCHEMBL25875489

Cc1ccc(OC(F)(F)C(C)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.42
BCHE P06276 1/20 0.38
TSHR P16473 2/20 0.37
GPR3 P46089 1/20 0.37
CYP3A4 P08684 1/20 0.37
TEAD4 Q15561 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.35
AR P10275 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
RELA Q04206 1/20 0.34
TP53 P04637 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549523 0.84 ACHE (0.44) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL20714605 0.82 CA1 (0.50) ACHETSHRCYP3A4TDP1ALDH1A1
SCHEMBL12200950 0.82 ACHE (0.42) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL10242545 0.81 ACHE (0.46) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL23029518 0.81 ACHE (0.46) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL10524397 0.80 ACHE (0.41) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL12012134 0.80 ALDH1A1 (0.45) TSHRCYP3A4TEAD4TDP1ALDH1A1
SCHEMBL13039942 0.79 CA4 (0.40) TSHRALDH1A1KCNH2
SCHEMBL10177249 0.78 ACHE (0.39) ACHEBCHETSHRGPR3CYP3A4
SCHEMBL91415 0.78 GPR3 (0.53) ACHEBCHETSHRGPR3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed