SCHEMBL25875530

SCHEMBL25875530

CC(F)(F)C(F)(F)Oc1cncc(Br)c1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.35
CHRNA4 P43681 1/20 0.35
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29041935 0.85 CHRNB2 (0.37) CHRNB2CHRNA4CYP11B1CYP11B2
SCHEMBL29041927 0.85 CYP11B1 (0.36) CHRNB2CHRNA4CYP11B1CYP11B2
SCHEMBL30459953 0.85 CHRNB2 (0.37) CHRNB2CHRNA4CYP11B1CYP11B2
SCHEMBL31370480 0.81 CHRNB2 (0.39) CHRNB2CHRNA4
SCHEMBL19552036 0.81
SCHEMBL25875532 0.80 CHRNB1 (0.34) CHRNB2CHRNA4
SCHEMBL25875527 0.79 PGR (0.31)
SCHEMBL29041953 0.76 TRPV1 (0.40) CHRNB2CHRNA4CYP11B1CYP11B2
SCHEMBL23540497 0.74 CHRNB2 (0.43) CHRNB2CHRNA4
SCHEMBL25875529 0.73 EPAS1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed