SCHEMBL25875532

SCHEMBL25875532

Cc1cncc(OC(F)(F)C(C)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRNB1 P11230 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRNB3 Q05901 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
ATM Q13315 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
HCAR2 Q8TDS4 1/20 0.32
VEGFA P15692 1/20 0.32
CYP3A4 P08684 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16289254 0.82 ATM (0.40) CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL14805691 0.80 CHRNB1 (0.37) CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL25875530 0.80 CHRNB2 (0.35) CHRNB2CHRNA4
SCHEMBL5749658 0.78 ALDH1A1 (0.37) CYP3A4
SCHEMBL25875492 0.72 ACHE (0.50)
SCHEMBL25875529 0.70 EPAS1 (0.31)
SCHEMBL11918259 0.70 ALDH1A1 (0.44) CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL25875489 0.70 ACHE (0.42) CYP3A4
SCHEMBL3253853 0.69 HCAR2 (0.39) CHRNB1CHRNB2CHRNB4CHRNA3CHRNA4
SCHEMBL29465753 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed