SCHEMBL25875843

SCHEMBL25875843

C=C(C)C(=O)Oc1ccc(-c2ccc3c(c2)oc2c(OC)c(OC(=O)C(=C)C)ccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.38
MAOA P21397 2/20 0.37
ADORA3 P0DMS8 1/20 0.37
MAOB P27338 1/20 0.37
ELANE P08246 1/20 0.37
HSD11B1 P28845 1/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ATM Q13315 1/20 0.35
ABCB1 P08183 1/20 0.35
TUBB4A P04350 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25873787 0.91 TUBB4A (0.42) ABCG2MAOAMAOBELANEKDM4E
SCHEMBL25876637 0.87 ADORA3 (0.35) ABCG2ADORA3ELANEHSD11B1KDM4E
SCHEMBL25875550 0.86 KMT2A (0.39) MAOAADORA3MAOBELANEKDM4E
SCHEMBL25875104 0.84 ALDH1A1 (0.40) ELANEKDM4EALDH1A1KMT2AMAPT
SCHEMBL25875842 0.84 ABCG2 (0.38) ABCG2MAOAADORA3MAOBHSD11B1
SCHEMBL25876144 0.84 ADORA3 (0.41) MAOAADORA3MAOBELANEKDM4E
SCHEMBL25907162 0.84 KDM4E (0.43) MAOAMAOBKDM4EALDH1A1KMT2A
SCHEMBL25875845 0.83 MAOA (0.34) MAOAMAOBCYP3A4TERTPOLB
SCHEMBL25876292 0.83 CYP2C9 (0.37) ABCG2ADORA3ELANEHSD11B1KDM4E
SCHEMBL25874472 0.82 MAOA (0.47) MAOAMAOBELANEKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed