SCHEMBL258778

SCHEMBL258778

Cc1ccc(S(=O)(=O)N2CC=CC2)cc1

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.66
HTT P42858 2/20 0.63
ALDH1A1 P00352 1/20 0.63
POLB P06746 1/20 0.63
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
GAA P10253 2/20 0.58
TSHR P16473 1/20 0.58
CYP2C19 P33261 1/20 0.58
LMNA P02545 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
MMP2 P08253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930631 0.87 PKM (0.61) PKMHTTALDH1A1POLBKMT2A
SCHEMBL1932281 0.84 PKM (0.65) PKMHTTALDH1A1POLBKMT2A
SCHEMBL2741402 0.83 PKM (0.64) PKMHTTALDH1A1POLBKMT2A
SCHEMBL8203532 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL699639 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL3303527 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL4537086 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL10724066 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL565301 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A
SCHEMBL3971438 0.83 PKM (0.88) PKMHTTALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947761-B Ruthenium carbene catalyst, composition containing ruthenium carbene catalyst, preparation method and application of ruthenium carbene catalyst 上海中化科技有限公司 2026-05-15 CN disclosed
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-08-05 US disclosed
WO-2025096300-A1 NOVEL METHODS FOR THE PREPARATION OF 3-AZABICYLCO[3.1,0]HEXANE-6-CARBOXAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 2025-05-08 WO disclosed
CN-119930696-A Imidazole coordinated ruthenium carbene olefin metathesis catalyst, preparation and application thereof 中国石油天然气股份有限公司 2025-05-06 CN disclosed
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) 2025-02-06 US disclosed
WO-2025008012-A1 PYRROLOQUINOLINES AND THEIR USE AS TUBULINE ASSEMBLY INHIBITORS UNIVERZITA PALACKEHO V OLOMOUCI (CZ) 2025-01-09 WO disclosed
US-12139504-B2 Vanadium alkylidene complex, synthesis and use thereof THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2024-11-12 US disclosed
EP-4433451-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF Ecole Nationale Supérieure de Chimie de Rennes (FR) 2024-09-25 EP disclosed
CN-109496214-B Crystal form and salt form of nitroimidazole compound and preparation method thereof 成都嘉葆药银医药科技有限公司 2024-09-10 CN disclosed
US-20240228519-A1 VANADIUM ALKYLIDENE COMPLEX, SYNTHESIS AND USE THEREOF THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2024-07-11 US disclosed
EP-1037897-A1 HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS Studiengesellschaft Kohle mbH (DE) 2000-09-27 EP disclosed
EP-0975622-A1 SELECTIVE OLEFIN METATHESIS OF BIFUNCTIONAL OR POLYFUNCTIONAL SUBSTRATES IN COMPRESSED CARBON DIOXIDE AS REACTION MEDIUM Studiengesellschaft Kohle mbH (DE) 2000-02-02 EP disclosed
US-6004956-A CHEMICAL INTERMEDIATES FOR BACTERICIDES BAYER AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
WO-1999028330-A1 HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS STUDIENGESELLSCHAFT KOHLE MBH (DE) 1999-06-10 WO disclosed
EP-0921129-A1 Highly active cationic ruthenium and osmium complexes for olefin metathesis reactions Studiengesellschaft Kohle mbH (DE) 1999-06-09 EP disclosed
EP-0551653-B1 Enantiomeric pure cis-2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation BAYER AG (DE) 1999-03-17 EP disclosed
WO-1998047891-A1 SELECTIVE OLEFIN METATHESIS OF BIFUNCTIONAL OR POLYFUNCTIONAL SUBSTRATES IN COMPRESSED CARBON DIOXIDE AS REACTION MEDIUM STUDIENGESELLSCHAFT KOHLE MBH (DE) 1998-10-29 WO disclosed
US-5532364-A FROM A DIHYDROPYRIDINE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 1996-07-02 US disclosed
US-5436334-A Enantiomerically pure 2-oxa-5,8-diazabicyclo[4.3.0]nonanes and process for their preparation BAYER AKTIENGESELLSCHAFT (DE) 1995-07-25 US disclosed
EP-0551653-A1 Enantiomeric pure 2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation BAYER AG (DE) 1993-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12139504-B2 Vanadium alkylidene complex, synthesis and use thereof VDAC3, CDV3, CBR3 PKM 80/4885HTT 1742/4885ALDH1A1 4675/4885
US-12377407-B2 Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis PPOX, CYBA, CYBB PKM 4372/4885HTT 2745/4885ALDH1A1 1395/4885
US-20240228519-A1 VANADIUM ALKYLIDENE COMPLEX, SYNTHESIS AND USE THEREOF VDAC3, CDV3, CBR3 PKM 80/4885HTT 1742/4885ALDH1A1 4675/4885
US-20250042854-A1 IMINIUM SALTS WITH A BARRALENE RING, CORRESPONDING RUTHENIUM COMPLEXES, AND USES THEREOF SQLE, SYMPK, FDFT1 PKM 4697/4885HTT 2939/4885ALDH1A1 1256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.