Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932281 | 0.95 | PKM (0.65) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL1930631 | 0.89 | PKM (0.61) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL13625328 | 0.84 | PKM (0.72) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL258778 | 0.83 | PKM (0.66) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL436674 | 0.83 | PKM (0.89) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL5564371 | 0.81 | KMT2A (0.86) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL31476293 | 0.81 | ALDH1A1 (0.92) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL15945283 | 0.81 | KMT2A (0.86) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL7645597 | 0.81 | KMT2A (0.86) | PKMALDH1A1POLBHTTKMT2A | |
| SCHEMBL18484219 | 0.81 | KMT2A (0.86) | PKMALDH1A1POLBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116302-B1 | Catalyst complex with a heterocyclic carbene ligand | UNIV OF NEW ORLEANS FOUND (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2016-08-25 | — | — | US | disclosed |
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. | 2016-08-25 | — | — | US | disclosed |
| US-9339805-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9339805-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9233365-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9233365-B2 | Catalyst complex with carbene ligand | MATERIA, INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | EVONIK INDUSTRIES AG (DE) | 2015-11-12 | — | — | US | disclosed |
| US-20150202610-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | MATERIA, INC. (US) | 2015-07-23 | — | — | US | disclosed |
| US-20120004418-A1 | Catalyst Complex With Carbene Ligand | MATERIA, INC. | 2012-01-05 | — | — | US | disclosed |
| US-7902389-B2 | Catalyst complex with carbene ligand | MATERIA, INC. | 2011-03-08 | — | — | US | disclosed |
| US-7902389-B2 | Catalyst complex with carbene ligand | MATERIA, INC. | 2011-03-08 | — | — | US | disclosed |
| US-20100160642-A1 | Catalyst Complex With Carbene Ligand | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160642-A1 | Catalyst Complex With Carbene Ligand | UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-7622590-B1 | Including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand; complexes are highly stable to air, moisture and thermal degradation; designed to efficiently carry out a variety of olefin metathesis reactions | UNIVERSITY OF NEW ORLEANS FOUNDATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622590-B1 | Including a metal atom having anionic ligands, at least one nucleophilic carbene ligand, and an alkylidene, vinylidene, or allenylidene ligand; complexes are highly stable to air, moisture and thermal degradation; designed to efficiently carry out a variety of olefin metathesis reactions | UNIVERSITY OF NEW ORLEANS FOUNDATION (US) | 2009-11-24 | — | — | US | disclosed |
| EP-2116302-A1 | Catalyst complex with a heterocyclic carbene ligand | University Of New Orleans Foundation (US) | 2009-11-11 | — | — | EP | disclosed |
| EP-1115491-B1 | CATALYST COMPLEX WITH PHENYLINDENYLIDENE LIGAND | UNIV NEW ORLEANS FOUNDATION (US) | 2009-08-05 | — | — | EP | disclosed |
| US-7348290-B2 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004418-A1 | Catalyst Complex With Carbene Ligand | ZC3H18, ZC3HAV1L, PDCD1LG2 | PKM 3618/4885ALDH1A1 3385/4885POLB 1027/4885 |
| US-20150202610-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | ZC3HAV1L, PDCD1LG2, ICOSLG | PKM 3652/4885ALDH1A1 3335/4885POLB 919/4885 |
| US-20100160642-A1 | Catalyst Complex With Carbene Ligand | ZC3H18, ZC3HAV1L, PDCD1LG2 | PKM 3618/4885ALDH1A1 3385/4885POLB 1027/4885 |
| US-20160243535-A1 | CATALYST COMPLEX WITH CARBENE LIGAND | ZC3HAV1L, PDCD1LG2, ICOSLG | PKM 3652/4885ALDH1A1 3335/4885POLB 919/4885 |
| US-20150322079-A1 | LOW CATALYST LOADING IN METATHESIS REACTIONS | APEX1, PMS2, MAX | PKM 1682/4885ALDH1A1 2091/4885POLB 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.